TheoryCSPT Sterile Compound Prep
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30 free CSPT Sterile Compound Prep questions
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CSPT Sterile Compound Prep
What is the required ISO classification inside a primary engineering control such as a laminar airflow workbench during sterile compounding?
Correct — D. ISO Class 5 is the required air quality classification for the direct compounding environment inside primary engineering controls to minimize particulate contamination during sterile preparation. -
CSPT Sterile Compound Prep
Which type of primary engineering control should be used when compounding hazardous sterile preparations?
Correct — C. A biological safety cabinet or compounding aseptic containment isolator provides both product protection and personnel protection through negative pressure and HEPA-filtered exhaust, making them appropriate for hazardous drug compounding. -
CSPT Sterile Compound Prep
What is the correct pressure differential relationship between a buffer room and an anteroom when compounding non-hazardous sterile preparations?
Correct — B. The buffer room must maintain positive pressure relative to the anteroom to prevent less clean air from entering the cleanest compounding area, protecting the sterile compounding environment. -
CSPT Sterile Compound Prep
Which component is essential for maintaining ISO Class 5 air quality in a laminar airflow workbench?
Correct — A. HEPA (High Efficiency Particulate Air) filters remove 99.97% of particles 0.3 microns or larger, creating the ISO Class 5 environment required for sterile compounding. -
CSPT Sterile Compound Prep
What is the minimum ISO classification required for an anteroom in a facility performing sterile compounding?
Correct — D. ISO Class 8 is the minimum classification for anterooms, providing a transitional environment between unclassified areas and the ISO Class 7 buffer room. -
CSPT Sterile Compound Prep
Which type of environmental monitoring detects living microorganisms in the compounding area?
Correct — C. Viable air sampling uses collection media to capture and culture living microorganisms from the air, allowing detection and quantification of microbial contamination. -
CSPT Sterile Compound Prep
What action should be taken when surface sampling results in a buffer room exceed established action levels?
Correct — B. When environmental monitoring results exceed action levels, the area must be cleaned, disinfected, and retested to ensure it returns to acceptable microbial limits before resuming compounding. -
CSPT Sterile Compound Prep
Which type of biological safety cabinet provides both product and personnel protection while venting HEPA-filtered air back into the room?
Correct — A. Class II Type A biological safety cabinets provide protection for both personnel and product, recirculating HEPA-filtered air back into the laboratory after removing particulates and potential contaminants. -
CSPT Sterile Compound Prep
How frequently must non-viable particle sampling be performed in an ISO Class 5 primary engineering control?
Correct — D. According to USP standards, non-viable particle sampling in ISO Class 5 environments must be performed at least every six months to verify air quality certification and proper HEPA filter function. -
CSPT Sterile Compound Prep
What is the primary purpose of a segregated compounding area?
Correct — A. A segregated compounding area contains ISO Class 5 primary engineering controls in a room that does not meet ISO Class 7 or 8 requirements, limited to compounding low-risk CSPs with 12-hour or less beyond use dates. -
CSPT Sterile Compound Prep
Which pressure relationship must exist in a containment segregated compounding area used for hazardous drugs?
Correct — B. Containment segregated compounding areas for hazardous drugs must maintain negative pressure relative to surrounding areas to prevent hazardous drug vapors or particles from escaping into adjacent spaces. -
CSPT Sterile Compound Prep
What is the minimum number of air changes per hour required in an ISO Class 7 buffer room?
Correct — A. ISO Class 7 buffer rooms require a minimum of 30 air changes per hour to maintain proper air quality and particulate removal necessary for supporting sterile compounding operations. -
CSPT Sterile Compound Prep
Which environmental monitoring method assesses the effectiveness of aseptic technique by testing the compounding personnel directly?
Correct — D. Gloved fingertip sampling evaluates whether personnel are maintaining proper aseptic technique during compounding by testing for microbial contamination on gloved fingers after compounding activities. -
CSPT Sterile Compound Prep
What type of primary engineering control uses a completely enclosed environment with glove ports for compounding?
Correct — C. Compounding aseptic isolators and compounding aseptic containment isolators are barrier systems with glove ports that provide a completely enclosed ISO Class 5 environment, separating the operator from the compounding area. -
CSPT Sterile Compound Prep
Which parameter tolerance must be continuously monitored and documented in a buffer room to ensure proper environmental control?
Correct — B. Temperature and pressure differentials must be continuously monitored in controlled environments to ensure they remain within specified tolerances for maintaining proper air quality and preventing contamination. -
CSPT Sterile Compound Prep
Why is food and drink prohibited in the buffer room and anteroom during sterile compounding operations?
Correct — A. Food and drink introduce particulates, microorganisms, and potential contaminants that can compromise the controlled environment and sterility of compounded preparations. -
CSPT Sterile Compound Prep
What is the primary difference between a horizontal and vertical laminar airflow workbench?
Correct — D. In a horizontal LAFW, HEPA-filtered air flows from the back toward the operator, while in a vertical LAFW, air flows downward from the top. Vertical flow provides better personnel protection and is preferred for hazardous compounding. -
CSPT Sterile Compound Prep
How should out-of-specification environmental monitoring results be documented?
Correct — C. All out-of-specification results must be thoroughly documented with corrective actions taken, investigation findings, and retesting results to maintain compliance and ensure patient safety. -
CSPT Sterile Compound Prep
Which feature distinguishes a compounding aseptic containment isolator from a standard compounding aseptic isolator?
Correct — B. A compounding aseptic containment isolator operates under negative pressure with externally vented HEPA-filtered exhaust to provide personnel and environmental protection when handling hazardous drugs. -
CSPT Sterile Compound Prep
What is the maximum humidity level recommended for maintaining proper environmental control in a buffer room?
Correct — A. Humidity in buffer rooms should typically be maintained at or below 60% relative humidity to prevent microbial growth, condensation, and degradation of compounded preparations while maintaining comfort and equipment function. -
CSPT Sterile Compound Prep
Which medication is classified as a high-alert drug requiring special handling procedures during compounding?
Correct — D. Concentrated potassium chloride is a high-alert medication that can cause serious harm if administered incorrectly, requiring special labeling and handling procedures during compounding. -
CSPT Sterile Compound Prep
What is the primary reason insulin is considered a narrow therapeutic index medication?
Correct — C. Insulin has a narrow therapeutic index because small changes in dose can result in significant blood glucose fluctuations, potentially causing hypoglycemia or hyperglycemia with serious clinical consequences. -
CSPT Sterile Compound Prep
Which factor would require a compounded sterile preparation containing amphotericin B to be stored in a light-protected container?
Correct — B. Amphotericin B is photosensitive and degrades when exposed to light, requiring light-protected containers or amber bags to maintain potency and stability throughout its beyond-use date. -
CSPT Sterile Compound Prep
What information found in a Safety Data Sheet is most critical for determining personal protective equipment requirements when compounding hazardous drugs?
Correct — A. The hazard classification section of the Safety Data Sheet identifies physical, health, and environmental hazards, which directly determine the type and level of PPE required for safe handling during compounding. -
CSPT Sterile Compound Prep
Which base solution is incompatible with phenytoin sodium injection due to precipitation risk?
Correct — D. Phenytoin sodium is only compatible with normal saline (0.9% sodium chloride). When mixed with dextrose-containing solutions, it precipitates due to decreased pH and reduced solubility. -
CSPT Sterile Compound Prep
According to package insert information, what is the maximum recommended concentration for peripheral administration of potassium chloride to minimize vein irritation?
Correct — C. Package inserts typically specify that potassium chloride for peripheral administration should not exceed 10 mEq per 100 mL (or 0.1 mEq/mL) to prevent venous irritation and phlebitis. -
CSPT Sterile Compound Prep
Which therapeutic class includes medications that require special containment procedures due to their antineoplastic properties?
Correct — B. Chemotherapy agents are antineoplastic drugs that can cause cellular damage and require special handling with closed system transfer devices, negative pressure techniques, and appropriate PPE to protect personnel. -
CSPT Sterile Compound Prep
What type of container closure system should be avoided when compounding paclitaxel due to leaching concerns?
Correct — A. Paclitaxel contains Cremophor EL, which can leach DEHP (di-2-ethylhexyl phthalate) from PVC containers and tubing. Non-DEHP or non-PVC materials such as glass, polyolefin, or DEHP-free bags must be used. -
CSPT Sterile Compound Prep
Which side effect is most commonly associated with rapid intravenous administration of vancomycin that requires rate control during compounding calculations?
Correct — D. Red man syndrome is a histamine-related reaction characterized by flushing, rash, and hypotension that occurs with rapid vancomycin infusion. Package inserts specify infusion times of at least 60 minutes to minimize this risk. -
CSPT Sterile Compound Prep
What is the primary contraindication for using lactated Ringer's solution as a diluent for ampicillin sodium?
Correct — C. Ampicillin sodium is incompatible with lactated Ringer's solution because the calcium ions in the solution can interact with the beta-lactam ring, leading to degradation and loss of potency.
CSPT Sterile Compound Prep sample questions
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Handling Packaging Storage And Disposal What type of container material should be selected when compounding paclitaxel to prevent leaching of plasticizers?
A. DEHP-free materials ✓
B. Standard PVC bags
C. Polyvinyl chloride containers
D. Latex-containing materials
Correct — A. Paclitaxel and other lipophilic drugs can leach DEHP from PVC containers. DEHP-free materials such as glass, polyolefin, or non-PVC bags must be used to maintain drug stability and patient safety.
Sterile Compounding Procedures A technician must perform media fill testing to demonstrate competency in aseptic technique. According to USP <797>, what is the minimum frequency for media fill testing for low-risk and medium-risk compounding?
A. Annually ✓
B. Every 6 months
C. Every 3 months
D. Monthly
Correct — A. Media fill testing must be performed initially during training and then at least annually for low-risk and medium-risk compounding to ensure continued competency in aseptic technique.
Handling Packaging Storage And Disposal Which storage temperature range defines controlled room temperature for compounded sterile preparations?
A. 15-20 degrees Celsius
B. 25-30 degrees Celsius
C. 10-15 degrees Celsius
D. 20-25 degrees Celsius ✓
Correct — D. Controlled room temperature is defined as 20-25 degrees Celsius (68-77 degrees Fahrenheit) according to USP standards for CSP storage.
About the CSPT Sterile Compound Prep test
The CSPT Sterile Compound Prep measures the Other knowledge you'll actually rely on — tested the way the real exam asks it, not with trick questions. Practising real CSPT Sterile Compound Prep-style questions, then sitting a full timed mock exam, is the fastest way to walk in knowing you'll pass.
You will be tested on
- Hazard identification and risk control
- Required workplace procedures
- Personal protective equipment and safe practice
- Compliance, reporting and documentation
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Topics in this question bank
Hazard identification and risk control
Required workplace procedures
Personal protective equipment and safe practice
Compliance, reporting and documentation
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