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PTCB PTCE Exam Questions & Answers 2026 (11–20)

PTCB PTCE practice questions and answers 2026. Tap an option to test yourself — you'll see the correct answer and a plain-English explanation for every question. Free, no login.

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  1. Q11Which of the following is NOT true regarding the use of electronic prescription records for controlled substances?

    • AThe pharmacy must be able to digitally sign and archive the controlled substance prescription.
    • BElectronic controlled substance records must be either easily readable, or able to be rendered into a format that any person can read.
    • CAll electronic records must be maintained for at least three years.
    • DThe electronic controlled substance record system must be audited or certified by a qualified third party.
    Show answer

    ✓ Correct answer: C. All electronic records must be maintained for at least three years.

    Records associated with electronic controlled substance prescriptions must be maintained for at least two years.

  2. Q12Which of the following controlled medications may be destroyed by a pharmacy with blanket authorization from the DEA to destroy controlled substances?

    • AControlled medication returned to the pharmacy due to a patient passing away
    • BOutdated controlled medications
    • CAll of the above
    • DRemaining controlled medication from a partially used ampule
    Show answer

    ✓ Correct answer: C. All of the above

    All of the above medications may be destroyed by a pharmacy with blanket authorization to destroy controlled substances. These medications must be destroyed using a method that results in leaving the medication in a state that it cannot be used. If a pharmacy technician is performing the destruction, they must have a pharmacist or nurse witness the action.

  3. Q13Pharmacy technicians can refer to the <code>________</code> Book to find out of if two drugs are equivalent.

    • ABlue
    • BGreen
    • COrange
    • DWhite
    Show answer

    ✓ Correct answer: C. Orange

    The primary reference for therapeutic equivalence is the FDA's Approved Drug Products with Therapeutic Equivalence Evaluations, commonly known as the Orange Book. It is the official source that provides standards, which dictate drug equivalence.

  4. Q14When considering a medication for inclusion on a preferred drug list, the committee takes all of the following into consideration EXCEPT:

    • ADrug safety
    • BDrug efficacy
    • CCost
    • DEase of pronunciation
    Show answer

    ✓ Correct answer: D. Ease of pronunciation

    When considering whether to include a specific drug for inclusion on a PDL, the committee examines drug safety, drug efficacy, and cost. However, the pronunciation of the medication's name has no bearing. A medication may be hard to say and still included because it is an effective medication at a reasonable cost!.

  5. Q15All of the following are situations that may require therapeutic drug monitoring, EXCEPT:

    • Athe healthcare provider suspects interaction of the drug with other drugs
    • Bthe healthcare provider is unsure if the patient is taking the medication as prescribed
    • Cthe patient is experiencing no adverse effects from the medication
    • Dthe patient needs to be slowly weaned off of a medication
    Show answer

    ✓ Correct answer: C. the patient is experiencing no adverse effects from the medication

    In addition to certain types of drugs, certain scenarios increase the need for therapeutic drug monitoring (TDM), such as: the patient is taking a normal dose, but doesn't seem to have a therapeutic response.<br/><br/>The healthcare provider is unsure if the patient is taking the medication like he/she ought.<br/><br/>The patient is experiencing many adverse effects from the medication.<br/><br/>The healthcare provider suspects interaction of the drug with other medications.<br/><br/>The patient needs to be slowly weaned off of a medication.

  6. Q16To reconstitute amoxicillin oral suspension, tap the bottle until the <code>________</code> flows freely. Add approximately ½ of the total amount of <code>________</code> for reconstitution and shake vigorously. Add remainder of the <code>________</code> and again shake vigorously.

    • Apowder; ethyl alcohol; powder
    • Bethyl alcohol; powder; powder
    • Cpowder; water; water
    • Dwater; powder; powder
    Show answer

    ✓ Correct answer: C. powder; water; water

    Amoxicillin oral suspension comes as a powder for reconstitution. Water must be added in a two-step fashion, and the bottle must be shaken vigorously to ensure thorough, uniform mixing. Ethyl alcohol is not used to reconstitute oral suspensions.

  7. Q17Which of the following over-the-counter (OTC) medications is classified as an antihistamine?

    • ADextromethorphan
    • BPseudoephedrine
    • CGuaifenesin
    • DLoratadine
    Show answer

    ✓ Correct answer: D. Loratadine

    Loratadine is an over-the-counter (OTC) medication that is classified as an antihistamine. Antihistamines are drugs that help to relieve allergy symptoms by blocking the action of histamine, a substance in the body that causes allergic reactions. Loratadine works by preventing histamine from binding to its receptors, thus reducing symptoms such as sneezing, itching, runny nose, and watery eyes.<br/><br/>Option A (Pseudoephedrine) is not classified as an antihistamine. Pseudoephedrine is a decongestant that helps to relieve nasal congestion by shrinking the blood vessels in the nasal passages. It does not have any direct effect on histamine or allergy symptoms.<br/><br/>Option C (Dextromethorphan) is not classified as an antihistamine either. Dextromethorphan is a cough suppressant that helps to alleviate coughing by acting on the cough center in the brain. It does not have any antihistamine properties.<br/><br/>Option D (Guaifenesin) is not an antihistamine medication. Guaifenesin is an expectorant that helps to thin and loosen mucus in the airways, making it easier to cough up. It is commonly used to relieve coughing associated with respiratory conditions, but it does not have any antihistamine effects.

  8. Q18Which of the tasks listed below is NOT a responsibility of a pharmacy technician?

    • Averifying drug deliveries
    • Bmaintaining inventory records
    • Cordering drugs
    • Ddispensing advice
    Show answer

    ✓ Correct answer: D. dispensing advice

    The job duties of a pharmacy technician encompass verifying drug deliveries, storing drugs, rotating stock, ordering drugs, and maintaining inventory records, among other tasks. However, pharmacy technicians are not authorized to counsel or provide medical information or advice to patients, as this falls under the purview of the pharmacist.

  9. Q19Among the options provided, which one is not categorized as a delayed-release dosage form?

    • ARepository
    • BTime release
    • CControlled release
    • DSublingual tablet
    Show answer

    ✓ Correct answer: D. Sublingual tablet

    A sublingual tablet is not categorized as a delayed-release dosage form because it is designed to dissolve under the tongue and be rapidly absorbed into the bloodstream. This bypasses the need for gastric absorption, allowing for quicker onset of action.<br/><br/>Option A (Controlled release): Controlled release dosage forms are designed to release the active ingredient slowly and steadily over an extended period of time. These formulations are commonly used to maintain consistent drug levels in the body and prolong the duration of therapeutic effect.<br/><br/>Option B (Repository): Repository dosage forms are designed to release the active ingredient gradually over time, typically from an implant or depot within the body. These formulations are often used for long-term drug delivery or to provide sustained release of a medication.<br/><br/>Option D (Time release): Time-release dosage forms are designed to release the active ingredient at specific intervals or time points, allowing for controlled drug delivery. These formulations are commonly used to provide sustained drug action and avoid frequent dosing.<br/><br/>In summary, while options A, B, and D are all categorized as delayed-release dosage forms, option C (sublingual tablet) is not.

  10. Q20Dr. Bobillo unintentionally neglected to mention the specific dosage of amoxicillin he prefers for his patient's infection.<br/><br/>What action would you take in this situation?

    • AGuess which strength he meant based on the directions.
    • BNone of the above
    • CAsk the pharmacist to call the doctor to see which strength he wanted.
    • DSend the patient away; there’s nothing you can do.
    Show answer

    ✓ Correct answer: C. Ask the pharmacist to call the doctor to see which strength he wanted.

    If a doctor omits the strength of a medication on the prescription, the best course of action is to contact the doctor to confirm the intended strength, unless the drug is only available in one strength.

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