CCRN practice questions and answers 2026. Tap an option to test yourself — you'll see the correct answer and a plain-English explanation for every question. Free, no login.
Q21A parent asks the Pediatric CCRN about varicella-zoster immune globulin. What is the most accurate statement to share?
✓ Correct answer: D. 'This is a pooled blood product with an excellent safety profile.'
Varicella immune globulin, like all immune globulin preparations, provides temporary passive immunity. It is derived from pooled blood donations but has an excellent safety profile. It is not synthetic, is not from a single donor, and does not transmit varicella to the child.
Q22Which of the following does NOT impair the body's ability to dissipate heat?
✓ Correct answer: D. Heart attack
A heart attack does not impair heat dissipation. The body's ability to release excess heat can be hindered by dehydration, excess clothing, and high ambient temperatures or humidity.
Q23Which of the following is a recognized contributing factor to hypothermia?
✓ Correct answer: A. Excessive alcohol consumption
Excessive alcohol intake impairs thermoregulation, increasing the risk of hypothermia.
Q24Which organism is most commonly responsible for causing neonatal urinary tract infections (UTIs)?
✓ Correct answer: D. Escherichia coli
UTIs in newborns are frequently accompanied by bacteremia and can result in long-term complications. Neonates with UTI should be evaluated for systemic infection and structural or functional urinary tract abnormalities. Escherichia coli is the most frequently implicated pathogen, accounting for up to 80% of neonatal UTIs. Klebsiella is the next most common, followed by Enterobacter and Citrobacter.
Q25Which of the following represents the body's primary (first line) defense against infection?
✓ Correct answer: D. Skin
The skin serves as the first line of defense against pathogens by providing a physical barrier. The second line of defense includes the inflammatory response, complement activation, and phagocytosis.
Q26On a standard chest X-ray, which structure appears black?
✓ Correct answer: C. Lungs
The lungs are filled primarily with air and therefore appear black on chest X-ray. The skeletal thorax appears white, and the heart and mediastinum appear gray.
Q27A nurse is reviewing the history of a 4-week-old infant diagnosed with bronchopulmonary dysplasia (BPD). Which historical finding is most consistent with this diagnosis?
✓ Correct answer: A. Prior mechanical ventilation
Bronchopulmonary dysplasia is an iatrogenic lung disease associated with positive-pressure mechanical ventilation used to treat lung disease in premature or critically ill newborns.
Q28In most respiratory disorders, which statement best describes physical activity?
✓ Correct answer: C. It needs to be carefully planned.
Patients with respiratory disorders are often easily fatigued. Physical activity must be planned carefully to conserve energy for the work of breathing and effective coughing, which are critical priorities in these patients.
Q29A nurse is performing an admission assessment on a newborn diagnosed with spina bifida (meningomyelocele). Which assessment action best identifies the most significant symptom of this condition?
✓ Correct answer: C. Checking for responses to painful stimuli from the torso downward
Newborns with meningomyelocele lack innervation below the level of the sac, which contains the meninges and spinal cord. They typically show diminished or absent pain responses in areas below the lesion.
Q30Which of the following correctly describes myxedema coma?
✓ Correct answer: B. It results from severe deficiency or complete absence of thyroid hormones
Myxedema coma is a life-threatening condition that develops when thyroid hormone levels are severely depleted or completely absent, leading to a profound slowing of metabolic processes.
Use the free CCRN Exam Prep 2026 Test sample, download the PDF, then unlock web-based timed mock exams for a full exam rehearsal.
Theory