HESI A2 practice questions and answers 2026. Tap an option to test yourself — you'll see the correct answer and a plain-English explanation for every question. Free, no login.
Q11A pediatric order reads: 12 mg/kg/day in 3 divided doses. The child weighs 22 kg. Available suspension is 60 mg/5 mL. How many mL is each dose?
✓ Correct answer: A. 7.33 mL
Daily dose = 12 × 22 = 264 mg; per dose = 264 ÷ 3 = 88 mg; volume = (88 ÷ 60) × 5 = 7.33 mL.
Q12A physician orders heparin 1,200 units/hour. The pharmacy bag contains 25,000 units in 250 mL NS. What pump rate in mL/hr is correct?
✓ Correct answer: A. 12 mL/hr
Concentration = 25,000 ÷ 250 = 100 units/mL; rate = 1,200 ÷ 100 = 12 mL/hr.
Q13To prepare 600 mL of 0.6% NaCl by mixing 0.45% NaCl (Solution A) and 0.9% NaCl (Solution B), how many mL of Solution A are needed?
✓ Correct answer: C. 400 mL
By alligation: parts of A = 0.9 − 0.6 = 0.3; parts of B = 0.6 − 0.45 = 0.15; ratio A:B = 2:1; A = (2/3) × 600 = 400 mL.
Q14A patient's fluid intake-to-output ratio must not exceed 3:2. If recorded output is 840 mL over 8 hours, what is the maximum allowable intake for that period?
✓ Correct answer: A. 1260 mL
Maximum intake = (3/2) × 840 = 1.5 × 840 = 1260 mL, derived directly from the 3:2 ratio constraint.
Q15A nurse administers an infusion at 42 drops/min using tubing with a drop factor of 15 gtt/mL. How many mL/hour is the patient receiving?
✓ Correct answer: D. 168 mL/hr
mL/hr = (drops/min × 60) ÷ drop factor = (42 × 60) ÷ 15 = 2520 ÷ 15 = 168 mL/hr.
Q16Read the following passage: 'Researchers now understand that chronic sleep deprivation does not merely cause fatigue; it fundamentally impairs the prefrontal cortex's regulatory functions, diminishing emotional control and risk-assessment capabilities. Paradoxically, severely sleep-deprived individuals often rate their own performance as adequate, unable to perceive their cognitive deficits.' Which inference is BEST supported by this passage?
✓ Correct answer: B. A sleep-deprived person may confidently make poor clinical decisions without awareness of impairment
Inference requires combining stated facts: impaired risk-assessment plus the inability to perceive one's own deficits logically implies a person would make poor decisions while feeling confident — a conclusion not stated outright but directly supported.
Q17A medication label states: 'For external use only. Apply a thin layer to the affected area twice daily. Keep away from eyes, mouth, and open wounds.' A patient asks a nurse whether they can use the cream on a paper cut on their finger. Based solely on the written directions, what should the nurse advise?
✓ Correct answer: A. The cream should not be used on the cut because open wounds are listed as an area to avoid
Following written directions means applying the explicit text: 'open wounds' are listed as areas to avoid, and a paper cut qualifies as an open wound.
Q18Passage: 'Urban emergency departments increasingly serve as the primary healthcare contact for uninsured patients. While this ensures immediate access to care, it strains department resources, extends wait times for all patients, and drives up costs that are absorbed system-wide. Some administrators advocate for linking ED visits to community health navigators who can connect patients with primary care.' What is the MAIN IDEA of this passage?
✓ Correct answer: A. Overreliance on EDs for primary care creates systemic problems that require coordinated solutions
The main idea encompasses all details: the passage describes the problem of ED overuse AND introduces a proposed solution, making the broader systemic framing the correct main idea rather than any single detail.
Q19Passage: 'The author of the hospital's new triage protocol writes with clipped, imperative sentences: each step numbered, each condition bracketed by precise thresholds, no passive voice, no hedging language.' What is the author's most likely PURPOSE in using this style?
✓ Correct answer: B. To ensure rapid, unambiguous decision-making under high-stress conditions
Author's purpose is inferred from stylistic choices: imperative, numbered, threshold-specific language in a triage context signals the goal is speed and clarity in high-pressure situations, not persuasion, credential display, or entertainment.
Q20A clinical study summary states: 'Patients who received the intervention showed a statistically significant reduction in systolic blood pressure (p < 0.05). However, the sample was drawn exclusively from patients at a single urban academic hospital.' What is the BEST inference about the applicability of these findings?
✓ Correct answer: D. The limited sample source may restrict how broadly the results apply
Inference in scientific reading requires recognizing that a single-site sample limits external validity — a conclusion the passage implies through its caveat without stating it directly.
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