HomeHESI A2 Exam & Prep 2026Questions 21–30
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HESI A2 Exam Questions & Answers 2026 (21–30)

HESI A2 practice questions and answers 2026. Tap an option to test yourself — you'll see the correct answer and a plain-English explanation for every question. Free, no login.

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  1. Q21In the sentence 'The physician's prognosis was guarded, suggesting the patient's recovery would be slow and uncertain,' what does the word 'guarded' most nearly mean as used here?

    • ADefended from outside threat
    • BProtected from disclosure
    • COfficially documented in the chart
    • DCautiously uncertain and not optimistic
    Show answer

    ✓ Correct answer: D. Cautiously uncertain and not optimistic

    Vocabulary in context: the surrounding phrase 'slow and uncertain recovery' defines 'guarded' as a clinical synonym for cautiously pessimistic or uncertain, not its everyday physical-protection meaning.

  2. Q22Passage: 'Critics of mandatory nurse-to-patient staffing ratios argue that rigid numerical limits reduce administrative flexibility and may lead hospitals to leave shifts understaffed rather than exceed the ratio. Proponents counter that without enforceable standards, market pressures consistently push staffing below safe thresholds.' What tone BEST characterizes this passage?

    • ABalanced and analytical
    • BAlarmed and one-sided
    • CEnthusiastic and persuasive
    • DSatirical and dismissive
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    ✓ Correct answer: A. Balanced and analytical

    Author's tone is determined by how both sides are presented: the passage gives equal weight to critics and proponents without advocating for either, establishing a balanced, analytical tone.

  3. Q23A pre-operative instruction form reads: 'Do not eat or drink anything after midnight the night before your procedure. This includes water, gum, and hard candy. Brush your teeth normally but do not swallow. Arrive 90 minutes before your scheduled procedure time.' A patient's procedure is at 10:00 a.m. At what time should the patient arrive?

    • A8:30 a.m.
    • B8:00 a.m.
    • C9:30 a.m.
    • D9:00 a.m.
    Show answer

    ✓ Correct answer: A. 8:30 a.m.

    Following written directions requires applying the arithmetic: 10:00 a.m. minus 90 minutes equals 8:30 a.m.

  4. Q24Passage: 'Unlike the clean moral binaries of early public health campaigns, contemporary health literacy materials must navigate a landscape where misinformation and credible evidence share the same digital channels, audiences distrust institutional voices, and urgency competes with nuance.' What supporting detail does the author use to develop the idea that modern health communication is more complex?

    • AInstitutional voices have always faced public skepticism
    • BEarly campaigns relied on radio and print media
    • CMisinformation and credible evidence occupy the same platforms, complicating audience discernment
    • DDigital channels are less trustworthy than print sources
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    ✓ Correct answer: C. Misinformation and credible evidence occupy the same platforms, complicating audience discernment

    Identifying supporting details requires selecting the detail that directly supports the stated claim of increased complexity — the co-presence of misinformation and evidence on shared platforms is explicitly cited as a complicating factor.

  5. Q25In the sentence 'The nurse practitioner provided a comprehensive overview of the patient's postoperative regimen,' what does 'regimen' most nearly mean?

    • AA government-approved medical protocol
    • BA summary of the surgical procedure
    • CA strict military-style discipline program
    • DA structured plan or course of treatment
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    ✓ Correct answer: D. A structured plan or course of treatment

    Vocabulary in context: 'regimen' in a clinical setting refers to a prescribed plan of care or treatment schedule, which fits the postoperative context described.

  6. Q26Passage: 'Hand hygiene compliance rates in hospitals remain stubbornly below recommended levels despite decades of education campaigns. Studies consistently show that time pressure, inconvenient placement of dispensers, and perceived low risk of transmission in certain moments are the primary behavioral drivers of non-compliance.' Which statement is a SUPPORTING DETAIL rather than the main idea?

    • AHand hygiene compliance is an ongoing challenge in hospital settings
    • BInconvenient dispenser placement is one factor driving non-compliance
    • CDecades of efforts have failed to reach recommended compliance levels
    • DEducation alone has not been sufficient to solve the compliance problem
    Show answer

    ✓ Correct answer: B. Inconvenient dispenser placement is one factor driving non-compliance

    A supporting detail is a specific piece of evidence backing the broader claim — dispenser placement is one particular behavioral driver cited, while the other options reflect broader thematic claims or conclusions.

  7. Q27A patient consent form includes this clause: 'By signing below, you acknowledge that you have received and understood this information. Your signature does not waive any rights you hold under applicable law, nor does it release the facility from liability for negligence.' A patient asks: 'If I sign, can the hospital avoid responsibility if a nurse makes a careless mistake?' Based solely on this text, what is the correct answer?

    • ANo, the form explicitly states it does not release the facility from liability for negligence
    • BThe form is ambiguous on this point
    • COnly if the patient initials the negligence clause separately
    • DYes, signing the form releases the hospital from all liability
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    ✓ Correct answer: A. No, the form explicitly states it does not release the facility from liability for negligence

    Following written directions and reading comprehension: the clause explicitly states the signature does not release the facility from liability for negligence, making the answer directly derivable from the text.

  8. Q28Passage: 'The proliferation of direct-to-consumer genetic testing has outpaced the clinical infrastructure needed to support it. Many individuals now receive probabilistic risk data about serious conditions without access to genetic counselors who can contextualize those findings.' What is the author's most likely PURPOSE in writing this passage?

    • ATo discourage consumers from purchasing genetic tests
    • BTo argue that genetic counselors are unnecessary in the digital age
    • CTo praise the medical advances made possible by consumer genomics
    • DTo highlight a gap between the availability of genetic information and the support systems needed to interpret it
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    ✓ Correct answer: D. To highlight a gap between the availability of genetic information and the support systems needed to interpret it

    Author's purpose: the passage identifies a problem (data availability without interpretive support) without prescribing a solution, which signals an informative-analytical purpose — raising awareness of the gap rather than advocating a specific position.

  9. Q29A patient education pamphlet contains this sentence: 'Patients with renal insufficiency should avoid prolonged use of NSAIDs, as these medications can further compromise kidney function.' What is the MAIN IDEA of this sentence?

    • ANSAIDs are dangerous for all patients regardless of kidney function
    • BShort-term NSAID use is always safe for patients with renal insufficiency
    • CPatients with reduced kidney function are at risk of further harm from extended NSAID use
    • DKidney disease is primarily caused by NSAID overuse
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    ✓ Correct answer: C. Patients with reduced kidney function are at risk of further harm from extended NSAID use

    The main idea is the central claim: the sentence warns specifically about the risk of further kidney damage from prolonged NSAIDs in patients who already have renal insufficiency, not a blanket prohibition for all patients.

  10. Q30Passage: 'A new nurse orients to a medical-surgical floor. Her preceptor tells her the unit uses a paper sign-out form; the posted protocol, however, specifies an electronic handoff tool. When the nurse asks which to follow, the preceptor says, 'We all use paper here.' The unit's official policy states: Written protocols supersede verbal instructions and informal unit practices in all patient safety matters.' Based on the written policy, what should the nurse do?

    • AFollow the preceptor's verbal instruction because the preceptor has more experience
    • BUse whichever method she personally finds most efficient
    • CEscalate to hospital administration before taking any action
    • DFollow the electronic handoff protocol because the written policy requires written protocols to supersede informal practices
    Show answer

    ✓ Correct answer: D. Follow the electronic handoff protocol because the written policy requires written protocols to supersede informal practices

    Following written directions in a scenario-based question requires applying the explicitly stated rule: written protocols supersede verbal instructions and informal practices, so the electronic tool must be used regardless of local custom.

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